Stem Cell Transplant Clinical Research Trials

stem cell trialsA list of Stem Cell Transplant medical analysis trials actively recruiting affected person volunteers. Search for closest metropolis to search out extra detailed info on a analysis examine in your space.

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Found (81) medical trials

ANBL0032: Phase III Randomized Study of Chimeric Antibody 14.18 (Ch14.18) in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue

For extra info please go to: http://clinicaltrials.gov/ct2/show/NCT00026312,term=ANBL0032&rank=1

Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Myeloma

Busulfan Test Dose: If you agree to participate on this examine, you’ll obtain a check dose of busulfan by vein over about 60 minutes. This low-level check dose of busulfan will assist the physician resolve what dose of busulfan you’ll obtain throughout the examine. You will most …

Safety Study of Gene Modified Donor T-cells Following TCR Alpha Beta Depleted Stem Cell Transplant

This is a Phase 1/2 examine evaluating the security and feasibility of BPX-501 T cells infused after partially mismatched, associated, TCR alpha beta T cell depleted hematopoietic stem cell transplant (HSCT) in pediatric sufferers. The objective of this medical trial is to find out whether or not BPX-501 infusion can improve immune reconstitution …

Sonidegib and Lenalidomide After Stem Cell Transplant in Treating Patients With Multiple Myeloma

PRIMARY OBJECTIVES: I. To assess the whole response (CR) price with lenalidomide and sonidegib (LDE225) upkeep following an upfront single autologous stem cell transplant (SCT). SECONDARY OBJECTIVES: I. To assess the toxicity of lenalidomide and LDE225 when used as upkeep remedy in sufferers submit autologous SCT. II. To decide the …

Multivirus-specific T Cells for the Treatment of Virus Infections After Stem Cell Transplant

These VST strains have been made at Baylor College of Medicine from donors for different transplant sufferers or different regular donors a few of whom had been from the National Marrow Donor Program. All donors have been screened with the usual blood financial institution donor questionnaire, medical historical past and testing for infectious illness …

Determining the Feasibility of MLN9708 as Maintenance After Allogeneic Stem Cell Transplant for Multiple Myeloma

Although a number of myeloma is taken into account deadly, survival has dramatically improved during the last 20 years with the introduction of simpler therapy choices. Proteasome inhibitors have an anti-myeloma impact and are sometimes used as both preliminary therapy or at relapse in sufferers with a number of myeloma. MLN9708 is an orally bioavailable, …

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

This is a single arm dose discovering examine evaluating the security and efficacy of a BPX 501 infusion (T cells genetically modified with the inducible Caspase 9 suicide gene) of 3x10E6 to 1X10E7 cells/kg adopted by an AP1903 infusion on day 7 after mismatched, associated, T cell-depleted hematopoietic …

MSCs With or Without Peripheral Blood Stem Cell for Treatment of Poor Graft Function and Delayed Platelet Engraftment

Allogeneic hematopoietic stem cell transplantation(allo-HSCT) is the one treatment for a lot of hematologic illnesses. However, about 5-27% of sufferers would endure from poor graft perform (PGF) and extra recipients may develop delayed platelet engraftment (DPE) after allo-HSCT. These issues are related to appreciable mortality associated to infections or hemorrhagic issues. Treatment …

Study of Elotuzumab With Lenalidomide as Maintenance After Autologous Stem Cell Transplant (ASCT)

Study Drug Administration: If you might be discovered to be eligible to participate on this examine, you’ll begin receiving the examine medication after you will have recovered from the stem cell transplant. Each examine cycle is 28 days. You will obtain elotuzumab by vein over about 2-Four hours on Days …

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Ixazomib After Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma in Remission

PRIMARY OBJECTIVES: I. To decide the beneficial section II dose and assess the security of ixazomib when administered as post-transplant upkeep in mantle cell lymphoma. (Phase I) II. To assess preliminary proof of efficacy of ixazomib when administered as post-transplant upkeep in mantle cell lymphoma. (Phase II) SECONDARY OBJECTIVES: I.

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